Early Glomerular Hyperfiltration and Long-Term Kidney Outcomes in Type 1 Diabetes | Zendy

Mark E. Molitch | Zendy; Xiaoyu Gao | Zendy; Ionut Bebu | Zendy; Ian H. de Boer | Zendy; John M. Lachin | Zendy; Andrew D. Paterson | Zendy; Bruce A. Perkins | Zendy; Amy K. Saenger | Zendy; Michael W. Steffes | Zendy; Bernard Zinman | Zendy

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Early Glomerular Hyperfiltration and Long-Term Kidney Outcomes in Type 1 Diabetes

Author(s) -

Mark E. Molitch,

Xiaoyu Gao,

Ionut Bebu,

Ian H. de Boer,

John M. Lachin,

Andrew D. Paterson,

Bruce A. Perkins,

Amy K. Saenger,

Michael W. Steffes,

Bernard Zinman

Publication year - 2019

Publication title -

clinical journal of the american society of nephrology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.755

H-Index - 151

eISSN - 1555-905X

pISSN - 1555-9041

DOI - 10.2215/cjn.14831218

Subject(s) - medicine , glomerular hyperfiltration , interquartile range , renal function , urology , hazard ratio , diabetes mellitus , confidence interval , surgery , endocrinology , diabetic nephropathy

Glomerular hyperfiltration has been considered to be a contributing factor to the development of diabetic kidney disease (DKD). To address this issue, we analyzed GFR follow-up data on participants with type 1 diabetes undergoing 125 I-iothalamate clearance on entry into the Diabetes Control and Complications Trial (DCCT)/Epidemiology of Diabetes Interventions and Complications study.

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