Open AccessChimeric Antigen Receptor T Cell Therapy and the Kidney
Author(s) -
Kenar D. Jhaveri,
Mitchell H. Rosner
Publication year - 2018
Publication title -
clinical journal of the american society of nephrology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.755
H-Index - 151
eISSN - 1555-905X
pISSN - 1555-9041
DOI - 10.2215/cjn.12871117
Subject(s) - medicine , chimeric antigen receptor , cell therapy , receptor , antigen , kidney , immunology , immunotherapy , cancer research , cell , immune system , biochemistry , chemistry
T cells are critical in orchestrating the immune response and killing cells infected by pathogens. In 1989, Gross et al. ([1][1]) reported the experiments introducing the genetic code for an antibody recognition site into a cytotoxic T cell that imparted the ability to recognize a specific antigen.
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