Use of Postoperative Creatinine to Predict Sustained Kidney Injury in Patients Undergoing Mesothelioma Surgery | Zendy

Kenji Mizuguchi | Zendy; Aya Mitani | Zendy; Sushrut S. Waikar | Zendy; Peter J. Ireland | Zendy; Christia Panizales | Zendy; Gretchen Deluke | Zendy; David J. Sugarbaker | Zendy; Joseph V. Bonventre | Zendy; György Frendl | Zendy

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Use of Postoperative Creatinine to Predict Sustained Kidney Injury in Patients Undergoing Mesothelioma Surgery

Author(s) -

Kenji Mizuguchi,

Aya Mitani,

Sushrut S. Waikar,

Peter J. Ireland,

Christia Panizales,

Gretchen Deluke,

David J. Sugarbaker,

Joseph V. Bonventre,

György Frendl

Publication year - 2012

Publication title -

clinical journal of the american society of nephrology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.755

H-Index - 151

eISSN - 1555-905X

pISSN - 1555-9041

DOI - 10.2215/cjn.12401211

Subject(s) - medicine , acute kidney injury , kidney disease , creatinine , cohort , renal function , kidney , mesothelioma , surgery , urology , pathology

AKI leads to increased morbidity and mortality and progression to chronic kidney injury is a frequent consequence of AKI. Surgical treatment of mesothelioma is associated with increased risk for kidney injury. However, sustained kidney injury may limit therapeutic options for treating residual cancer. This study hypothesized that patients with significant serum creatinine (sCr) elevation within 48 hours of surgery would be at risk for sustained kidney injury. The goal was to determine the best acute sCr measure predictive of sustained kidney injury defined as a 50% increase in sCr from baseline measured 2-4 weeks after surgery.

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