GFR in Patients with β-Thalassemia Major | Zendy

Gai Milo | Zendy; Revital Feige Gross Nevo | Zendy; Idit Pazgal | Zendy; Anat GafterGvili | Zendy; Ofer Shpilberg | Zendy; Uzi Gafter | Zendy; A. Erman | Zendy; Pinhas Stark | Zendy

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GFR in Patients with β-Thalassemia Major

Author(s) -

Gai Milo,

Revital Feige Gross Nevo,

Idit Pazgal,

Anat GafterGvili,

Ofer Shpilberg,

Uzi Gafter,

A. Erman,

Pinhas Stark

Publication year - 2015

Publication title -

clinical journal of the american society of nephrology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.755

H-Index - 151

eISSN - 1555-905X

pISSN - 1555-9041

DOI - 10.2215/cjn.12181214

Subject(s) - renal function , medicine , creatinine , urology , kidney disease , thalassemia , glomerular hyperfiltration , inulin , cystatin c , endocrinology , kidney , diabetic nephropathy , chemistry , biochemistry

Patients with β-thalassemia major (TM) may have tubular dysfunction and glomerular dysfunction, primarily hyperfiltration, based on eGFR. Assessment of GFR based on serum creatinine concentration may overestimate GFR in these patients. This study sought to determine GFR by using inulin clearance and compare it with measured creatinine clearance (Ccr) and eGFR.

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