Collapsing Glomerulopathy in 19 Patients with Systemic Lupus Erythematosus or Lupus-Like Disease
Author(s) -
Steven Salvatore,
Laura Barisoni,
Andrew M. Herzenberg,
Praveen Chander,
Volker Nickeleit,
Surya V. Seshan
Publication year - 2012
Publication title -
clinical journal of the american society of nephrology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.755
H-Index - 151
eISSN - 1555-905X
pISSN - 1555-9041
DOI - 10.2215/cjn.11751111
Subject(s) - medicine , lupus nephritis , proteinuria , glomerulopathy , systemic lupus erythematosus , renal biopsy , nephrotic syndrome , gastroenterology , creatinine , pathology , biopsy , urology , kidney , disease
Collapsing glomerulopathy is a podocytopathy with segmental or global wrinkling and collapse of capillary walls and overlying epithelial cell proliferation. Idiopathic collapsing glomerulopathy is a distinct clinicopathologic entity with significant proteinuria, poor response to immunosuppressive therapy, and rapid progression to renal failure. Collapsing glomerulopathy is associated with viral infections, autoimmune disease, and drugs. This work presents the largest group of collapsing glomerulopathy in patients with SLE.
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