Two phosphAte taRGets in End-stage renal disease Trial (TARGET): A Randomized Controlled Trial
Author(s) -
Ron Wald,
Christian G. Rabbat,
Louis Girard,
Amit X. Garg,
Karthik Tennankore,
Jessica Tyrwhitt,
Andrew Smyth,
Andrea Rathe-Skafel,
Peggy Gao,
Andrea Mazzetti,
Jackie Bosch,
Andrew T. Yan,
Patrick S. Parfrey,
Braden Manns,
Michael Walsh
Publication year - 2017
Publication title -
clinical journal of the american society of nephrology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.755
H-Index - 151
eISSN - 1555-905X
pISSN - 1555-9041
DOI - 10.2215/cjn.10941016
Subject(s) - medicine , hyperphosphatemia , interquartile range , randomized controlled trial , phosphate binder , randomization , hemodialysis , confidence interval , phosphate , dialysis , clinical endpoint , lanthanum carbonate , gastroenterology , kidney disease , surgery , biochemistry , chemistry
Hyperphosphatemia is common among recipients of maintenance dialysis and is associated with a higher risk of mortality and cardiovascular events. A large randomized trial is needed to determine whether lowering phosphate concentrations with binders improves patient-important outcomes. To inform such an effort we conducted a pilot randomized controlled trial.
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