Use of Dried Plasma Spots for the Quantification of Iothalamate in Clinical Studies
Author(s) -
Andrew S. Hagan,
David Jones,
Rajiv Agarwal
Publication year - 2013
Publication title -
clinical journal of the american society of nephrology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.755
H-Index - 151
eISSN - 1555-905X
pISSN - 1555-9041
DOI - 10.2215/cjn.10471012
Subject(s) - dried blood , spots , hematocrit , medicine , confidence interval , limits of agreement , chromatography , dried blood spot , bland–altman plot , whole blood , nuclear medicine , chemistry , pathology
Although iothalamate clearances have been widely used to measure GFR, the need for transportation of plasma samples under refrigerated conditions obviates its use in resource-poor situations. Spots of blood or plasma dried on filter paper may provide a solution.
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