Sodium Thiosulfate Pharmacokinetics in Hemodialysis Patients and Healthy Volunteers | Zendy

Stefan Farese | Zendy; Emilie Stauffer | Zendy; Robert M. Kalicki | Zendy; Tatjana M. Hildebrandt | Zendy; Brigitte M. Frey | Zendy; Felix J. Frey | Zendy; Dominik E. Uehlinger | Zendy; Andreas Pasch | Zendy

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Sodium Thiosulfate Pharmacokinetics in Hemodialysis Patients and Healthy Volunteers

Author(s) -

Stefan Farese,

Emilie Stauffer,

Robert M. Kalicki,

Tatjana M. Hildebrandt,

Brigitte M. Frey,

Felix J. Frey,

Dominik E. Uehlinger,

Andreas Pasch

Publication year - 2011

Publication title -

clinical journal of the american society of nephrology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.755

H-Index - 151

eISSN - 1555-905X

pISSN - 1555-9041

DOI - 10.2215/cjn.10241110

Subject(s) - medicine , hemodialysis , sodium thiosulfate , pharmacokinetics , dialysis , bioavailability , renal function , urology , dosing , urine , pharmacology , chemistry , inorganic chemistry

Vascular calcification is a major cause of morbidity and mortality in dialysis patients. Human and animal studies indicate that sodium thiosulfate (STS) may prevent the progression of vascular calcifications. The pharmacokinetics of STS in hemodialysis patients has not been investigated yet.

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