z-logo
open-access-imgOpen Access
Biomarker Enhanced Risk Prediction for Adverse Outcomes in Critically Ill Patients Receiving RRT
Author(s) -
Francis Pike,
Raghavan Murugan,
Christopher Keener,
Paul M. Palevsky,
Anitha Vijayan,
Mark L. Unruh,
Kevin W. Finkel,
XiaoYan Wen,
John A. Kellum
Publication year - 2015
Publication title -
clinical journal of the american society of nephrology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.755
H-Index - 151
eISSN - 1555-905X
pISSN - 1555-9041
DOI - 10.2215/cjn.09911014
Subject(s) - medicine , renal replacement therapy , receiver operating characteristic , biomarker , confidence interval , acute kidney injury , veterans affairs , prospective cohort study , intensive care medicine , biochemistry , chemistry
Higher plasma concentrations of inflammatory and apoptosis markers in critically ill patients receiving RRT are associated with RRT dependence and death. This study objective was to examine whether plasma inflammatory (IL-6, -8, -10, and -18; macrophage migration inhibitory factor) and apoptosis (death receptor-5, tumor necrosis factor receptor I and II) biomarkers augment risk prediction of renal recovery and mortality compared with clinical models.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.
Having issues? You can contact us here
Accelerating Research

Address

John Eccles House
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom