Association of Serum Ig Free Light Chains with Mortality and ESRD among Patients with Nondialysis-Dependent CKD | Zendy

James Ritchie | Zendy; Lakhvir K. Assi | Zendy; Anne Burmeister | Zendy; Richard Hoefield | Zendy; Paul Cockwell | Zendy; Philip A. Kalra | Zendy

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Association of Serum Ig Free Light Chains with Mortality and ESRD among Patients with Nondialysis-Dependent CKD

Author(s) -

James Ritchie,

Lakhvir K. Assi,

Anne Burmeister,

Richard Hoefield,

Paul Cockwell,

Philip A. Kalra

Publication year - 2015

Publication title -

clinical journal of the american society of nephrology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.755

H-Index - 151

eISSN - 1555-905X

pISSN - 1555-9041

DOI - 10.2215/cjn.09660914

Subject(s) - medicine , hazard ratio , interquartile range , confidence interval , proportional hazards model , quartile , cohort , cohort study , kidney disease , renal function , prospective cohort study

High levels of serum polyclonal combined Ig free light chains are associated with inflammation and decreased excretory kidney function, and they are an independent risk factor for mortality. Whether combined Ig free light chain predicted mortality and progression to ESRD in a stages 3-5 CKD cohort was assessed.

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