Urinary Biomarkers and Progression of AKI in Patients with Cirrhosis
Author(s) -
Justin M. Belcher,
Guadalupe García–Tsao,
Arun J. Sanyal,
Heather ThiessenPhilbrook,
Aldo J. Peixoto,
Mark A. Perazella,
Naheed Ansari,
Joseph K. Lim,
Steven G. Coca,
Chirag R. Parikh
Publication year - 2014
Publication title -
clinical journal of the american society of nephrology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.755
H-Index - 151
eISSN - 1555-905X
pISSN - 1555-9041
DOI - 10.2215/cjn.09430913
Subject(s) - medicine , acute kidney injury , albuminuria , cirrhosis , gastroenterology , lipocalin , creatinine , urinary system , kidney disease
AKI is a common and severe complication in patients with cirrhosis. AKI progression was previously shown to correlate with in-hospital mortality. Therefore, accurately predicting which patients are at highest risk for AKI progression may allow more rapid and targeted treatment. Urinary biomarkers of structural kidney injury associate with AKI progression and mortality in multiple settings of AKI but their prognostic performance in patients with liver cirrhosis is not well known.
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