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Serum Soluble Urokinase-Type Plasminogen Activator Receptor Levels and Idiopathic FSGS in Children
Author(s) -
Margret Bock,
Heather E. Price,
Lorenzo Gallon,
Craig B. Langman
Publication year - 2013
Publication title -
clinical journal of the american society of nephrology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.755
H-Index - 151
eISSN - 1555-905X
pISSN - 1555-9041
DOI - 10.2215/cjn.07680712
Subject(s) - supar , medicine , proteinuria , nephrotic syndrome , urokinase receptor , kidney disease , plasminogen activator , gastroenterology , kidney , endocrinology
FSGS is the primary cause of childhood nephrotic syndrome leading to ESRD. Permeability factors, including circulating serum soluble urokinase-type plasminogen activator receptor (suPAR), have been postulated as putative causes in adults with primary FSGS. Similar results have yet to be proven in children.

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