Effects of Dopamine Donor Pretreatment on Graft Survival after Kidney Transplantation: A Randomized Trial
Author(s) -
Peter Schnuelle,
Wilhelm H. Schmitt,
Christel Weiß,
Antje Habicht,
Lutz Renders,
Martin Zeier,
Felix Drüschler,
Katharina Heller,
Przemyslaw Pisarski,
Bernhard Banas,
Bernhard K. Krämer,
Matthias Jung,
Kai Lopau,
Christoph J. Olbricht,
H. Weihprecht,
Peter Schenker,
Johan W. de Fijter,
Benito A. Yard,
Urs Benck
Publication year - 2017
Publication title -
clinical journal of the american society of nephrology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.755
H-Index - 151
eISSN - 1555-905X
pISSN - 1555-9041
DOI - 10.2215/cjn.07600716
Subject(s) - medicine , hazard ratio , randomized controlled trial , transplantation , confidence interval , dopamine , renal function , urology , censoring (clinical trials) , kidney transplantation , anesthesia , surgery , pathology
Donor dopamine improves initial graft function after kidney transplantation due to antioxidant properties. We investigated if a 4 µ g/kg per minute continuous dopamine infusion administered after brain-death confirmation affects long-term graft survival and examined the exposure-response relationship with treatment duration.
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