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Factors Influencing Treatment of Atypical Hemolytic Uremic Syndrome
Author(s) -
Carla Nester,
Richard J. Smith
Publication year - 2014
Publication title -
clinical journal of the american society of nephrology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.755
H-Index - 151
eISSN - 1555-905X
pISSN - 1555-9041
DOI - 10.2215/cjn.07540714
Subject(s) - atypical hemolytic uremic syndrome , medicine , eculizumab , population , immunology , disease , complement system , antibody , environmental health
Over the past 2 decades, tremendous strides have been made in our understanding of the ultra-rare disease atypical hemolytic uremic syndrome (aHUS). At the center of this progress has been the discovery that the majority of patients with aHUS (>50%) carry causative DNA variants in alternate

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