Association of APOL1 Genotype with Renal Histology among Black HIV-Positive Patients Undergoing Kidney Biopsy | Zendy

Mohamed G. Atta | Zendy; Michelle M. Estrella | Zendy; Karl Skorecki | Zendy; Jeffrey B. Kopp | Zendy; Cheryl A. Winkler | Zendy; Walter G. Wasser | Zendy; Revital Shemer | Zendy; Lorraine C. Racusen | Zendy; Michael Kuperman | Zendy; Matthew C. Foy | Zendy; Gregory M. Lucas | Zendy; Derek M. Fine | Zendy

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Association of APOL1 Genotype with Renal Histology among Black HIV-Positive Patients Undergoing Kidney Biopsy

Author(s) -

Mohamed G. Atta,

Michelle M. Estrella,

Karl Skorecki,

Jeffrey B. Kopp,

Cheryl A. Winkler,

Walter G. Wasser,

Revital Shemer,

Lorraine C. Racusen,

Michael Kuperman,

Matthew C. Foy,

Gregory M. Lucas,

Derek M. Fine

Publication year - 2015

Publication title -

clinical journal of the american society of nephrology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.755

H-Index - 151

eISSN - 1555-905X

pISSN - 1555-9041

DOI - 10.2215/cjn.07490715

Subject(s) - medicine , genotype , nephropathy , odds ratio , logistic regression , kidney disease , renal biopsy , biopsy , endocrinology , biology , genetics , diabetes mellitus , gene

Prior studies have shown that the APOL1 risk alleles are associated with a greater risk of HIV-associated nephropathy and FSGS among blacks who are HIV positive. We sought to determine whether the APOL1 high-risk genotype incrementally improved the prediction of these underlying lesions beyond conventional clinical factors.

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