Calcium and Phosphorus Regulatory Hormones and Risk of Incident Symptomatic Kidney Stones
Author(s) -
Eric N. Taylor,
Andrew N. Hoofnagle,
Gary C. Curhan
Publication year - 2015
Publication title -
clinical journal of the american society of nephrology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.755
H-Index - 151
eISSN - 1555-905X
pISSN - 1555-9041
DOI - 10.2215/cjn.07060714
Subject(s) - medicine , parathyroid hormone , vitamin d and neurology , endocrinology , kidney stones , creatinine , prospective cohort study , odds ratio , body mass index , calcium , hormone , kidney , gastroenterology
Calcium and phosphorus regulatory hormones may contribute to the pathogenesis of calcium nephrolithiasis. However, there has been no prospective study to date of plasma hormone levels and risk of kidney stones. This study aimed to examine independent associations between plasma levels of 1,25-dihydroxyvitamin D (1,25[OH]2D), 25-hydroxyvitamin D, 24,25-dihydroxyvitamin D, fibroblast growth factor 23 (FGF23), parathyroid hormone, calcium, phosphate, and creatinine and the subsequent risk of incident kidney stones.
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