Sevelamer Versus Calcium-Based Binders for Treatment of Hyperphosphatemia in CKD
Author(s) -
Leena Patel,
Lisa Bernard,
Grahame J. Elder
Publication year - 2015
Publication title -
clinical journal of the american society of nephrology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.755
H-Index - 151
eISSN - 1555-905X
pISSN - 1555-9041
DOI - 10.2215/cjn.06800615
Subject(s) - sevelamer , medicine , hyperphosphatemia , confidence interval , gastroenterology , dialysis , adverse effect , meta analysis , hemodialysis , calcium
People with CKD stages 3-5 and on dialysis (5D) have dramatically increased mortality, which has been associated with hyperphosphatemia in many studies. Oral phosphate binders are commonly prescribed to lower serum phosphate. We conducted an updated meta-analysis of the noncalcium-based binder (non-CBB) sevelamer versus CBBs in CKD stages 3-5D.
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