Membranoproliferative Glomerulonephritis Secondary to Monoclonal Gammopathy
Author(s) -
Sanjeev Sethi,
Ladan Zand,
Nelson Leung,
Richard J. Smith,
Dragan Jevremonic,
Sandra M. Herrmann,
Fernando C. Fervenza
Publication year - 2010
Publication title -
clinical journal of the american society of nephrology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.755
H-Index - 151
eISSN - 1555-905X
pISSN - 1555-9041
DOI - 10.2215/cjn.06760909
Subject(s) - medicine , membranoproliferative glomerulonephritis , monoclonal gammopathy of undetermined significance , cryoglobulinemia , immunofixation , monoclonal , glomerulonephritis , pathology , gammopathy , multiple myeloma , renal biopsy , biopsy , immunology , monoclonal antibody , hepatitis c virus , kidney , antibody , virus
Membranoproliferative glomerulonephritis (MPGN) is an immune complex-mediated glomerulonephritis characterized by subendothelial and mesangial deposition of immune complexes. Autoimmune diseases and chronic infections, such as hepatitis C, are commonly recognized causes of MPGN; however, monoclonal gammopathy is a less widely recognized cause of MPGN.
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