Open AccessModeled Urea Distribution Volume and Mortality in the HEMO Study
Author(s) -
John T. Daugirdas,
Tom Greene,
Thomas A. Depner,
Nathan W. Levin,
Glenn M. Chertow
Publication year - 2011
Publication title -
clinical journal of the american society of nephrology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.755
H-Index - 151
eISSN - 1555-905X
pISSN - 1555-9041
DOI - 10.2215/cjn.06340710
Subject(s) - medicine , volume (thermodynamics) , urea , volume of distribution , intensive care medicine , cardiology , biochemistry , thermodynamics , chemistry , physics , pharmacokinetics
In the Hemodialysis (HEMO) Study, observed small decreases in achieved equilibrated Kt/V(urea) were noncausally associated with markedly increased mortality. Here we examine the association of mortality with modeled volume (V(m)), the denominator of equilibrated Kt/V(urea).
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