(1-34) Parathyroid Hormone Infusion Acutely Lowers Fibroblast Growth Factor 23 Concentrations in Adult Volunteers
Author(s) -
Orlando M. Gutiérrez,
Kelsey Smith,
Allison Barchi-Chung,
Neha M. Patel,
Tamara Isakova,
Myles Wolf
Publication year - 2012
Publication title -
clinical journal of the american society of nephrology
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 2.755
H-Index - 151
eISSN - 1555-905X
pISSN - 1555-9041
DOI - 10.2215/cjn.06240611
Subject(s) - medicine , parathyroid hormone , fibroblast growth factor 23 , endocrinology , growth hormone , hormone , calcium
Fibroblast growth factor 23 (FGF23) regulates phosphorus and vitamin D metabolism. Parathyroid hormone (PTH) infusion for 24 hours stimulated FGF23 secretion in healthy volunteers. The extent to which this was due to a direct stimulatory effect of PTH versus an indirect effect of increasing 1,25-dihydroxyvitamin D [1,25(OH)(2)D] levels was unclear.
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