Serum Fetuin-A Levels Are Associated with Vascular Calcifications and Predict Cardiovascular Events in Renal Transplant Recipients
Author(s) -
Céline Maréchal,
Georg Schlieper,
Pauline Nguyen,
Thilo Krüger,
Emmanuel Coche,
Annie Robert,
Jorgen Floege,
Éric Goffin,
Michel Jadoul,
Olivier Devuyst
Publication year - 2011
Publication title -
clinical journal of the american society of nephrology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.755
H-Index - 151
eISSN - 1555-905X
pISSN - 1555-9041
DOI - 10.2215/cjn.06150710
Subject(s) - medicine , hazard ratio , biomarker , fetuin , cardiology , confidence interval , proportional hazards model , gastroenterology , biochemistry , chemistry , microbiology and biotechnology , glycoprotein , biology
Vascular calcifications predict cardiovascular disease, the major cause of death in renal transplant recipients (RTRs). We studied the determinants of fetuin-A, a potent circulating calcification inhibitor encoded by the AHSG gene, and tested its association with vascular calcifications and long-term survival and cardiovascular events (CVEs) in RTRs.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom