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Serum Fetuin-A Levels Are Associated with Vascular Calcifications and Predict Cardiovascular Events in Renal Transplant Recipients
Author(s) -
Céline Maréchal,
Georg Schlieper,
Pauline Nguyen,
Thilo Krüger,
Emmanuel Coche,
Annie Robert,
Jorgen Floege,
Éric Goffin,
Michel Jadoul,
Olivier Devuyst
Publication year - 2011
Publication title -
clinical journal of the american society of nephrology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.755
H-Index - 151
eISSN - 1555-905X
pISSN - 1555-9041
DOI - 10.2215/cjn.06150710
Subject(s) - medicine , hazard ratio , biomarker , fetuin , cardiology , confidence interval , proportional hazards model , gastroenterology , biochemistry , chemistry , microbiology and biotechnology , glycoprotein , biology
Vascular calcifications predict cardiovascular disease, the major cause of death in renal transplant recipients (RTRs). We studied the determinants of fetuin-A, a potent circulating calcification inhibitor encoded by the AHSG gene, and tested its association with vascular calcifications and long-term survival and cardiovascular events (CVEs) in RTRs.

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