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Glomerular Density and Volume in Renal Biopsy Specimens of Children with Proteinuria Relative to Preterm Birth and Gestational Age
Author(s) -
Kentaro Koike,
Yohei Ikezumi,
Nobuo Tsuboi,
Go Kanzaki,
Kotaro Haruhara,
Yusuke Okabayashi,
Takaya Sasaki,
Makoto Ogura,
Akihiko Saitoh,
Takashi Yokoo
Publication year - 2017
Publication title -
clinical journal of the american society of nephrology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.755
H-Index - 151
eISSN - 1555-905X
pISSN - 1555-9041
DOI - 10.2215/cjn.05650516
Subject(s) - medicine , low birth weight , renal biopsy , birth weight , gestational age , nephrotic syndrome , urology , focal segmental glomerulosclerosis , proteinuria , biopsy , glomerulosclerosis , gastroenterology , kidney , pregnancy , genetics , biology
A low total nephron number, which is associated with low birth weight (LBW), may indicate increased susceptibility to early-onset renal diseases in children. However, few studies have assessed renal biopsy findings in LBW children. We examined the relationship between LBW and glomerular density (GD) and/or glomerular volume (GV) in renal biopsy samples as a surrogate for total nephron number.

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