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GFR is scaled to body surface area (S), whereas hemodialysis dosage is scaled to total body water (V). Scaling to metabolic rate (M) or liver size (L) has also been proposed.

clinical journal of the american society of nephrology

Scaling of Measured Glomerular Filtration Rate in Kidney Donor Candidates by Anthropometric Estimates of Body Surface Area, Body Water, Metabolic Rate, or Liver Size