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Association of Serum Bicarbonate with Incident Functional Limitation in Older Adults
Author(s) -
Robert H. Yenchek,
Joachim H. Ix,
Dena E. Rifkin,
Michael G. Shlipak,
Mark J. Sarnak,
Melissa García,
Kushang V. Patel,
Suzanne Satterfield,
Tamara B. Harris,
Anne B. Newman,
Linda F. Fried
Publication year - 2014
Publication title -
clinical journal of the american society of nephrology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.755
H-Index - 151
eISSN - 1555-905X
pISSN - 1555-9041
DOI - 10.2215/cjn.05480614
Subject(s) - medicine , interquartile range , hazard ratio , renal function , kidney disease , proportional hazards model , bicarbonate , prospective cohort study , body mass index , diabetes mellitus , physical therapy , endocrinology , confidence interval
Cross-sectional studies have found that low serum bicarbonate is associated with slower gait speed. Whether bicarbonate levels independently predict the development of functional limitation has not been previously studied. Whether bicarbonate was associated with incident persistent lower extremity functional limitation and whether the relationship differed in individuals with and without CKD were assessed in participants in the Health, Aging, and Body Composition study, a prospective study of well functioning older individuals

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