The Effect of Extended Release Niacin on Markers of Mineral Metabolism in CKD | Zendy

Rakesh Malhotra | Zendy; Ronit Katz | Zendy; Andrew N. Hoofnagle | Zendy; Andrew G. Bostom | Zendy; Dena E. Rifkin | Zendy; Ruth McBride | Zendy; Jeffrey L. Probstfield | Zendy; Geoffrey A. Block | Zendy; Joachim H. Ix | Zendy

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The Effect of Extended Release Niacin on Markers of Mineral Metabolism in CKD

Author(s) -

Rakesh Malhotra,

Ronit Katz,

Andrew N. Hoofnagle,

Andrew G. Bostom,

Dena E. Rifkin,

Ruth McBride,

Jeffrey L. Probstfield,

Geoffrey A. Block,

Joachim H. Ix

Publication year - 2017

Publication title -

clinical journal of the american society of nephrology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.755

H-Index - 151

eISSN - 1555-905X

pISSN - 1555-9041

DOI - 10.2215/cjn.05440517

Subject(s) - medicine , niacin , metabolism , endocrinology

Niacin downregulates intestinal sodium-dependent phosphate transporter 2b expression and reduces intestinal phosphate transport. Short-term studies have suggested that niacin lowers serum phosphate concentrations in patients with CKD and ESRD. However, the long-term effects of niacin on serum phosphate and other mineral markers are unknown.

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