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Addition of Plasmapheresis Decreases the Incidence of Acute Antibody-Mediated Rejection in Sensitized Patients with Strong Donor-Specific Antibodies
Author(s) -
Enver Akalin,
Rajani Dinavahi,
Rex Friedlander,
Scott Ames,
Graciela de Boccardo,
Vinita Sehgal,
Bernd SchroCombining Diaeresisppel,
Madhu Bhaskaran,
Susan Lerner,
Marileno Fotino,
Barbara Murphy,
Jonathan S. Bromberg
Publication year - 2008
Publication title -
clinical journal of the american society of nephrology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.755
H-Index - 151
eISSN - 1555-905X
pISSN - 1555-9041
DOI - 10.2215/cjn.05321107
Subject(s) - plasmapheresis , medicine , antibody , thymoglobulin , complement dependent cytotoxicity , immunology , donor specific antibodies , desensitization (medicine) , panel reactive antibody , incidence (geometry) , gastroenterology , flow cytometry , transplantation , kidney transplantation , monoclonal antibody , antibody dependent cell mediated cytotoxicity , physics , receptor , optics
The objective of this study was to investigate the effects of desensitization protocols using intravenous Ig with or without plasmapheresis in patients with donor-specific anti-HLA antibodies on prevention of antibody-mediated rejection and downregulation of donor-specific antibodies.

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