Frequent Hemodialysis Schedules Are Associated with Reduced Levels of Dialysis-induced Cardiac Injury (Myocardial Stunning) | Zendy

Helen J. Jefferies | Zendy; Bhupinder Virk | Zendy; Brigitte Schiller | Zendy; John Moran | Zendy; Christopher W. McIntyre | Zendy

Open Access

Frequent Hemodialysis Schedules Are Associated with Reduced Levels of Dialysis-induced Cardiac Injury (Myocardial Stunning)

Author(s) -

Helen J. Jefferies,

Bhupinder Virk,

Brigitte Schiller,

John Moran,

Christopher W. McIntyre

Publication year - 2011

Publication title -

clinical journal of the american society of nephrology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.755

H-Index - 151

eISSN - 1555-905X

pISSN - 1555-9041

DOI - 10.2215/cjn.05200610

Subject(s) - medicine , hemodialysis , myocardial stunning , dialysis , stunning , cardiology , intensive care medicine , ischemia

Recurrent hemodialysis (HD)-induced ischemic cardiac injury (myocardial stunning) is common and associated with high ultrafiltration (UF) requirements, intradialytic hypotension, long-term loss of systolic function, increased likelihood of cardiovascular events, and death. More frequent HD regimens are associated with lower UF requirements and improved hemodynamic tolerability, improved cardiovascular outcomes, and reduced mortality compared with conventional thrice-weekly HD. This study investigated the hypothesis that modification of UF volume and rate with more frequent HD therapies would abrogate dialysis-induced myocardial stunning.

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