Effect of Urate-Lowering Therapy on Cardiovascular and Kidney Outcomes | Zendy

Qi Chen | Zendy; Zi Wang | Zendy; Jingwei Zhou | Zendy; Zhenjie Chen | Zendy; Yan Li | Zendy; Shichao Li | Zendy; Hukang Zhao | Zendy; Sunil V. Badve | Zendy; Jicheng Lv | Zendy

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Effect of Urate-Lowering Therapy on Cardiovascular and Kidney Outcomes

Author(s) -

Qi Chen,

Zi Wang,

Jingwei Zhou,

Zhenjie Chen,

Yan Li,

Shichao Li,

Hukang Zhao,

Sunil V. Badve,

Jicheng Lv

Publication year - 2020

Publication title -

clinical journal of the american society of nephrology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.755

H-Index - 151

eISSN - 1555-905X

pISSN - 1555-9041

DOI - 10.2215/cjn.05190420

Subject(s) - medicine , confidence interval , adverse effect , kidney disease , randomized controlled trial , relative risk , meta analysis , regimen , intensive care medicine

Several clinical practice guidelines noted the potential benefits of urate-lowering therapy on cardiovascular disease and CKD progression; however, the effect of this regimen remains uncertain. In this systematic review, we aimed to evaluate the efficacy of urate-lowering therapy on major adverse cardiovascular events, all-cause mortality, kidney failure events, BP, and GFR.

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