Open AccessEstimated Effect of Epoetin Dosage on Survival among Elderly Hemodialysis Patients in the United States
Author(s) -
Yi Zhang,
Mae Thamer,
Dennis J. Cotter,
James S. Kaufman,
Miguel A. Hernán
Publication year - 2009
Publication title -
clinical journal of the american society of nephrology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.755
H-Index - 151
eISSN - 1555-905X
pISSN - 1555-9041
DOI - 10.2215/cjn.05071008
Subject(s) - medicine , hazard ratio , hemodialysis , dose , proportional hazards model , confidence interval , confounding , cumulative dose , dialysis , relative risk , epoetin alfa , hemoglobin
The common finding that low achieved hemoglobin in observational studies and high target hemoglobin in randomized trials each were associated with increased mortality and high epoetin dosage has suggested the possibility that high epoetin dosage might explain the increased mortality risk.