Three-Year Outcomes of a Randomized, Double-Blind, Placebo-Controlled Study Assessing Safety and Efficacy of C1 Esterase Inhibitor for Prevention of Delayed Graft Function in Deceased Donor Kidney Transplant Recipients | Zendy

Edmund Huang | Zendy; Ashley Vo | Zendy; Jua Choi | Zendy; Noriko Ammerman | Zendy; Kathlyn Lim | Zendy; Supreet Sethi | Zendy; Irene Kim | Zendy; Sanjeev Kumar | Zendy; Reiad Najjar | Zendy; Alice Peng | Zendy; Stanley C. Jordan | Zendy

Open Access

Three-Year Outcomes of a Randomized, Double-Blind, Placebo-Controlled Study Assessing Safety and Efficacy of C1 Esterase Inhibitor for Prevention of Delayed Graft Function in Deceased Donor Kidney Transplant Recipients

Author(s) -

Edmund Huang,

Ashley Vo,

Jua Choi,

Noriko Ammerman,

Kathlyn Lim,

Supreet Sethi,

Irene Kim,

Sanjeev Kumar,

Reiad Najjar,

Alice Peng,

Stanley C. Jordan

Publication year - 2019

Publication title -

clinical journal of the american society of nephrology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.755

H-Index - 151

eISSN - 1555-905X

pISSN - 1555-9041

DOI - 10.2215/cjn.04840419

Subject(s) - medicine , placebo , randomized controlled trial , confidence interval , renal function , incidence (geometry) , surgery , cumulative incidence , gastroenterology , transplantation , pathology , physics , alternative medicine , optics

Delayed graft function is related to ischemia-reperfusion injury and may be complement dependent. We previously reported from a randomized, placebo-controlled trial that treatment with C1 esterase inhibitor was associated with a shorter duration of delayed graft function and higher eGFR at 1 year. Here, we report longer-term outcomes from this trial.

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