Urinary Cystatin C as a Potential Risk Marker for Cardiovascular Disease and Chronic Kidney Disease in Patients with Obesity and Metabolic Syndrome
Author(s) -
Noriko SatohAsahara,
Takayoshi Suganami,
Takafumi Majima,
Kazuhiko Kotani,
Yasuhisa Kato,
Rika Araki,
Kazunori Koyama,
Taiichiro Okajima,
Makito Tanabe,
Mariko Oishi,
Akihiro Himeno,
Shigeo Kono,
Akira Sugawara,
Masakazu Hattori,
Yoshihiro Ogawa,
Akira Shimatsu
Publication year - 2010
Publication title -
clinical journal of the american society of nephrology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.755
H-Index - 151
eISSN - 1555-905X
pISSN - 1555-9041
DOI - 10.2215/cjn.04830610
Subject(s) - medicine , cystatin c , metabolic syndrome , obesity , disease , kidney disease , urinary system , endocrinology , renal function
Obesity and metabolic syndrome (MS) increase the risk of cardiovascular disease (CVD), chronic kidney disease (CKD), and all-cause mortality. Serum cystatin C (S-CysC), a marker of GFR, has been shown to be associated with CVD and CKD. This study was designed to elucidate the association of urinary CysC (U-CysC), a marker of renal tubular dysfunction, with CVD and CKD risk factors in patients with obesity and MS.
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