Clinical, Genetic, and Urinary Factors Associated with Uromodulin Excretion
Author(s) -
Stéphan Troyanov,
Catherine DelmasFrenette,
Guillaume Bollée,
Sonia Youhanna,
Vanessa Bruat,
Philip Awadalla,
Olivier Devuyst,
François Madore
Publication year - 2015
Publication title -
clinical journal of the american society of nephrology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.755
H-Index - 151
eISSN - 1555-905X
pISSN - 1555-9041
DOI - 10.2215/cjn.04770415
Subject(s) - tamm–horsfall protein , medicine , excretion , uric acid , creatinine , population , endocrinology , hyperuricemia , urinary system , physiology , environmental health
The urinary excretion of uromodulin is influenced by common variants in the UMOD gene, and it may be related to NaCl retention and hypertension. Levels of uromodulin are also dependent of the renal function, but other determinants remain unknown.
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