Glomerular Density in Renal Biopsy Specimens Predicts the Long-Term Prognosis of IgA Nephropathy | Zendy

Nobuo Tsuboi | Zendy; Tetsuya Kawamura | Zendy; Kentaro Koike | Zendy; Hideo Okonogi | Zendy; Keita Hirano | Zendy; Akihiko Hamaguchi | Zendy; Yoichi Miyazaki | Zendy; Makoto Ogura | Zendy; Kensuke Joh | Zendy; Yasunori Utsunomiya | Zendy; Tatsuo Hosoya | Zendy

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Glomerular Density in Renal Biopsy Specimens Predicts the Long-Term Prognosis of IgA Nephropathy

Author(s) -

Nobuo Tsuboi,

Tetsuya Kawamura,

Kentaro Koike,

Hideo Okonogi,

Keita Hirano,

Akihiko Hamaguchi,

Yoichi Miyazaki,

Makoto Ogura,

Kensuke Joh,

Yasunori Utsunomiya,

Tatsuo Hosoya

Publication year - 2009

Publication title -

clinical journal of the american society of nephrology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.755

H-Index - 151

eISSN - 1555-905X

pISSN - 1555-9041

DOI - 10.2215/cjn.04680709

Subject(s) - medicine , renal biopsy , biopsy , nephropathy , glomerulosclerosis , renal function , urology , proteinuria , pathology , kidney , glomerulonephritis , nephrology , fibrosis , predictive value of tests , gastroenterology , endocrinology , diabetes mellitus

An early histopathologic predictor of the renal prognosis, before the occurrence of advanced glomerular sclerosis/interstitial fibrosis and/or apparent renal dysfunction, remains to be established in IgA nephropathy (IgAN). This study aimed to determine whether the glomerular density (GD; nonsclerotic glomerular number per renal cortical area) of biopsy specimens obtained at an early stage of IgAN could predict the long-term renal outcome.

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