Open AccessCirculating Endotoxemia
Author(s) -
Chris McIntyre,
L. Harrison,
Mohamed Tarek Eldehni,
Helen J. Jefferies,
CheukChun Szeto,
Stephen G. John,
Mhairi K. Sigrist,
James O. Burton,
Daljit K. Hothi,
Shvan Korsheed,
Paul Owen,
Ka-Bik Lai,
P. K. T. Li
Publication year - 2011
Publication title -
clinical journal of the american society of nephrology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.755
H-Index - 151
eISSN - 1555-905X
pISSN - 1555-9041
DOI - 10.2215/cjn.04610510
Subject(s) - medicine , kidney disease , systemic inflammation , dialysis , cardiology , hemodialysis , renal function , pathophysiology , sepsis , gastroenterology , circulatory system , pulse wave velocity , inflammation , blood pressure
Translocated endotoxin derived from intestinal bacteria has a wide range of adverse effects on cardiovascular (CV) structure and function, driving systemic inflammation, atherosclerosis and oxidative stress. This study's aim was to investigate endotoxemia across the spectrum of chronic kidney disease (CKD).