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Treatment of Acute Renal Failure Secondary to Multiple Myeloma with Chemotherapy and Extended High Cut-Off Hemodialysis
Author(s) -
Colin A. Hutchison,
A.R. Bradwell,
Mark Cook,
Kolitha Basnayake,
Supratik Basu,
Stephen Harding,
John Hattersley,
Neil D. Evans,
Mike J Chappel,
Paul D. Sampson,
Lukas Foggensteiner,
Dwomoa Adu,
Paul Cockwell
Publication year - 2009
Publication title -
clinical journal of the american society of nephrology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.755
H-Index - 151
eISSN - 1555-905X
pISSN - 1555-9041
DOI - 10.2215/cjn.04590908
Subject(s) - medicine , digoxin , heart failure , intensive care medicine , multiple myeloma , chemotherapy , hemodialysis , cardiology
Extended hemodialysis using a high cut-off dialyzer (HCO-HD) removes large quantities of free light chains in patients with multiple myeloma. However, the clinical utility of this method is uncertain. This study assessed the combination of chemotherapy and HCO-HD on serum free light chain concentrations and renal recovery in patients with myeloma kidney (cast nephropathy) and dialysis-dependent acute renal failure.

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