Primary, Nonsyndromic Vesicoureteric Reflux and Nephropathy in Sibling Pairs | Zendy

H Lambert | Zendy; A. Keith Stewart | Zendy; Ambrose Gullett | Zendy; Heather J. Cordell | Zendy; Sue Malcolm | Zendy; Sally Feather | Zendy; Judith A. Goodship | Zendy; Timothy H.J. Goodship | Zendy; Adrian S. Woolf | Zendy

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Primary, Nonsyndromic Vesicoureteric Reflux and Nephropathy in Sibling Pairs

Author(s) -

H Lambert,

A. Keith Stewart,

Ambrose Gullett,

Heather J. Cordell,

Sue Malcolm,

Sally Feather,

Judith A. Goodship,

Timothy H.J. Goodship,

Adrian S. Woolf

Publication year - 2011

Publication title -

clinical journal of the american society of nephrology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.755

H-Index - 151

eISSN - 1555-905X

pISSN - 1555-9041

DOI - 10.2215/cjn.04580510

Subject(s) - medicine , vesicoureteric reflux , cystography , sibling , reflux nephropathy , vesicoureteral reflux , pediatrics , urinary system , index case , reflux , disease , psychology , developmental psychology

Primary vesicoureteric reflux (VUR) can coexist with reflux nephropathy (RN) and impaired renal function. VUR appears to be an inherited condition and is reported in approximately one third of siblings of index cases. The objective was to establish a DNA collection and clinical database from U.K. families containing affected sibling pairs for future VUR genetics studies. The cohort's clinical characteristics have been described.

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