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Associations between Intensity of RRT, Inflammatory Mediators, and Outcomes
Author(s) -
Raghavan Murugan,
XiaoYan Wen,
Christopher Keener,
Francis Pike,
Paul M. Palevsky,
Mark L. Unruh,
Kevin W. Finkel,
Anitha Vijayan,
Michele Elder,
YiFan Chen,
John A. Kellum
Publication year - 2015
Publication title -
clinical journal of the american society of nephrology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.755
H-Index - 151
eISSN - 1555-905X
pISSN - 1555-9041
DOI - 10.2215/cjn.04560514
Subject(s) - medicine , renal replacement therapy , odds ratio , confidence interval , biomarker , intensive care , prospective cohort study , dialysis , intensive care medicine , biochemistry , chemistry
Critically ill patients requiring RRT have higher circulating plasma concentrations of inflammatory and apoptosis markers that are associated with subsequent RRT dependence and death. Whether intensive dosing of RRT is associated with changes in specific mediators is unknown.

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