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Copeptin, a Surrogate Marker of Vasopressin, Is Associated with Disease Severity in Autosomal Dominant Polycystic Kidney Disease
Author(s) -
Esther Meijer,
Stephan J. L. Bakker,
Eric J. van der Jagt,
Gerjan Navis,
Paul E. de Jong,
Joachim Struck,
Ron T. Gansevoort
Publication year - 2010
Publication title -
clinical journal of the american society of nephrology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.755
H-Index - 151
eISSN - 1555-905X
pISSN - 1555-9041
DOI - 10.2215/cjn.04560510
Subject(s) - copeptin , medicine , autosomal dominant polycystic kidney disease , urine osmolality , endocrinology , vasopressin , albuminuria , renal function , renal blood flow , nephrology , urinary system , urology , kidney
Experimental studies suggest a detrimental role for vasopressin in the pathogenesis of autosomal dominant polycystic kidney disease (ADPKD). However, it is unknown whether endogenous vasopressin concentration is associated with disease severity in patients with ADPKD.

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