History-Adjusted Marginal Structural Analysis of the Association between Hemoglobin Variability and Mortality among Chronic Hemodialysis Patients
Author(s) -
Steven M. Brunelli,
Marshall M. Joffe,
Rubeen Israni,
Wei Yang,
Steven Fishbane,
Jeffrey S. Berns,
Harold I. Feldman
Publication year - 2008
Publication title -
clinical journal of the american society of nephrology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.755
H-Index - 151
eISSN - 1555-905X
pISSN - 1555-9041
DOI - 10.2215/cjn.04281007
Subject(s) - medicine , hemoglobin , marginal structural model , confounding , hazard ratio , confidence interval , dialysis , hemodialysis , cohort study , anemia
Hemoglobin variability is common among dialysis patients, and has been associated with increased mortality. The causal nature of this association has been difficult to ascertain because of potential time-dependent confounding, for which traditional statistical methods do not control.
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