Efficacy of Levofloxacin in the Treatment of BK Viremia | Zendy

Belinda T. Lee | Zendy; Steven Gabardi | Zendy; Mónica Grafals | Zendy; Robert Hofmann | Zendy; Enver Akalin | Zendy; Aws Aljanabi | Zendy; Didier A. Mandelbrot | Zendy; Deborah Adey | Zendy; Eliot Heher | Zendy; Pang-Yen Fan | Zendy; Sarah S. Conte | Zendy; Christine Dyer-Ward | Zendy; Anil Chandraker | Zendy

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Efficacy of Levofloxacin in the Treatment of BK Viremia

Author(s) -

Belinda T. Lee,

Steven Gabardi,

Mónica Grafals,

Robert Hofmann,

Enver Akalin,

Aws Aljanabi,

Didier A. Mandelbrot,

Deborah Adey,

Eliot Heher,

Pang-Yen Fan,

Sarah S. Conte,

Christine Dyer-Ward,

Anil Chandraker

Publication year - 2014

Publication title -

clinical journal of the american society of nephrology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.755

H-Index - 151

eISSN - 1555-905X

pISSN - 1555-9041

DOI - 10.2215/cjn.04230413

Subject(s) - medicine , viremia , bk virus , immunosuppression , levofloxacin , viral load , placebo , creatinine , renal function , gastroenterology , kidney transplantation , immunology , transplantation , antibiotics , virus , pathology , alternative medicine , microbiology and biotechnology , biology

BK virus reactivation in kidney transplant recipients can lead to progressive allograft injury. Reduction of immunosuppression remains the cornerstone of treatment for active BK infection. Fluoroquinolone antibiotics are known to have in vitro antiviral properties, but the evidence for their use in patients with BK viremia is inconclusive. The objective of the study was to determine the efficacy of levofloxacin in the treatment of BK viremia.

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