High Dose Omega-3 Fatty Acid Administration and Skeletal Muscle Protein Turnover in Maintenance Hemodialysis Patients | Zendy

Serpil Müge Değer | Zendy; Adriana M. Hung | Zendy; Charles D. Ellis | Zendy; Cindy Booker | Zendy; Aihua Bian | Zendy; Guanhua Chen | Zendy; Naji N. Abumrad | Zendy; T. Alp İkizler | Zendy

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High Dose Omega-3 Fatty Acid Administration and Skeletal Muscle Protein Turnover in Maintenance Hemodialysis Patients

Author(s) -

Serpil Müge Değer,

Adriana M. Hung,

Charles D. Ellis,

Cindy Booker,

Aihua Bian,

Guanhua Chen,

Naji N. Abumrad,

T. Alp İkizler

Publication year - 2016

Publication title -

clinical journal of the american society of nephrology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.755

H-Index - 151

eISSN - 1555-905X

pISSN - 1555-9041

DOI - 10.2215/cjn.04150415

Subject(s) - medicine , interquartile range , c reactive protein , wasting , placebo , gastroenterology , hemodialysis , endocrinology , inflammation , pathology , alternative medicine

Protein energy wasting and systemic inflammation are prevalent in maintenance hemodialysis (MHD) patients. Omega-3 (ω-3) fatty acids have anti-inflammatory properties and have been shown to improve protein homeostasis. We hypothesized that administration of high-dose (2.9 g/d) ω-3 would be associated with decreased muscle protein breakdown in MHD patients with systemic inflammation.

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