Open AccessRelationship of Circulating Anti-C3b and Anti-C1q IgG to Lupus Nephritis and Its Flare
Author(s) -
Daniel J. Birmingham,
Joshua E. Bitter,
Ezinne G. Ndukwe,
Sarah Dials,
Terese Gullo,
Sara Conroy,
Haikady N. Nagaraja,
Brad H. Rovin,
Lee A. Hebert
Publication year - 2015
Publication title -
clinical journal of the american society of nephrology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.755
H-Index - 151
eISSN - 1555-905X
pISSN - 1555-9041
DOI - 10.2215/cjn.03990415
Subject(s) - lupus nephritis , medicine , autoantibody , nephritis , systemic lupus erythematosus , immunology , antibody , gastroenterology , disease
Autoantibodies to complement C1q (anti-C1q) are associated with the diagnosis of lupus nephritis. In this study, we compare anti-C1q IgG with another complement autoantibody, anti-C3b IgG, as a biomarker of lupus nephritis and lupus nephritis flare.
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