Higher Levels of Leflunomide Are Associated with Hemolysis and Are not Superior to Lower Levels for BK Virus Clearance in Renal Transplant Patients
Author(s) -
Nicolae Leca,
Kimberly A. Muczynski,
Jonathan Ashley Jefferson,
Ian H. de Boer,
Jolanta Kowalewska,
Elizabeth Kendrick,
Raimund Pichler,
Connie L. Davis
Publication year - 2008
Publication title -
clinical journal of the american society of nephrology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.755
H-Index - 151
eISSN - 1555-905X
pISSN - 1555-9041
DOI - 10.2215/cjn.03930907
Subject(s) - leflunomide , medicine , bk virus , renal function , nephropathy , microangiopathy , urology , transplantation , gastroenterology , creatinine , hemolysis , kidney transplantation , endocrinology , diabetes mellitus , rheumatoid arthritis
Leflunomide use in renal transplantation has been increasing. Outcome correlation and safety data are still to be refined. The goals of this study were to report one center's experience with leflunomide, specifically the correlation of leflunomide levels with the outcomes of BK nephropathy and the observed toxic effects during the treatment with leflunomide.
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