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Does Heparin Coating Improve Patency or Reduce Infection of Tunneled Dialysis Catheters?
Author(s) -
Gaurav Jain,
Michael Allon,
Souheil Saddekni,
Jill-Finkel Barker,
Ivan D. Maya
Publication year - 2009
Publication title -
clinical journal of the american society of nephrology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.755
H-Index - 151
eISSN - 1555-905X
pISSN - 1555-9041
DOI - 10.2215/cjn.03920609
Subject(s) - medicine , catheter , heparin , bacteremia , surgery , hazard ratio , dialysis catheter , thrombosis , hemodialysis , dialysis , internal jugular vein , hemodialysis catheter , anticoagulant , confidence interval , anesthesia , microbiology and biotechnology , biology , antibiotics
Tunneled dialysis catheters are prone to frequent malfunction and infection. Catheter thrombosis occurs despite prophylactic anticoagulant locks. Catheter thrombi may also serve as a nidus for catheter infection, thereby increasing the risk of bacteremia. Thus, heparin coating of catheters may reduce thrombosis and infection. This study evaluated whether heparin-coated hemodialysis catheters have fewer infections or greater cumulative survival than noncoated catheters.

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