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Kinetic Model of Phosphorus Mobilization during and after Short and Conventional Hemodialysis
Author(s) -
Baris U. Agar,
Alp Akonur,
Ying-Cheng Lo,
Alfred K. Cheung,
John K. Leypoldt
Publication year - 2011
Publication title -
clinical journal of the american society of nephrology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.755
H-Index - 151
eISSN - 1555-905X
pISSN - 1555-9041
DOI - 10.2215/cjn.03860411
Subject(s) - hemodialysis , phosphorus , medicine , extracellular fluid , compartment (ship) , concordance correlation coefficient , kinetics , phosphate , volume of distribution , distribution (mathematics) , urology , surgery , extracellular , chemistry , biochemistry , pharmacokinetics , mathematics , statistics , mathematical analysis , oceanography , organic chemistry , physics , quantum mechanics , geology
The kinetics of plasma phosphorus (inorganic phosphorus or phosphate) during hemodialysis treatments cannot be explained by conventional one- or two-compartment models; previous approaches have been limited by assuming that the distribution of phosphorus is confined to classical intracellular and extracellular fluid compartments. In this study a novel pseudo one-compartment model, including phosphorus mobilization from a large second compartment, was proposed and evaluated.

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