Individualized Therapy to Prevent Bone Mineral Density Loss after Kidney and Kidney-Pancreas Transplantation | Zendy

Rahul Mainra | Zendy; Grahame J. Elder | Zendy

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Individualized Therapy to Prevent Bone Mineral Density Loss after Kidney and Kidney-Pancreas Transplantation

Author(s) -

Rahul Mainra,

Grahame J. Elder

Publication year - 2009

Publication title -

clinical journal of the american society of nephrology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.755

H-Index - 151

eISSN - 1555-905X

pISSN - 1555-9041

DOI - 10.2215/cjn.03770609

Subject(s) - medicine , bone mineral , urology , femoral neck , transplantation , bone remodeling , osteoporosis , kidney transplantation , bone density , calcitriol , teriparatide , renal osteodystrophy , surgery , kidney disease , vitamin d and neurology

Most patients who undergo kidney or kidney-pancreas transplantation have renal osteodystrophy, and immediately after transplantation bone mineral density (BMD) commonly falls. Together, these abnormalities predispose to an increased fracture incidence. Bisphosphonate or calcitriol therapy can preserve BMD after transplantation, but although bisphosphonates may be more effective, they pose potential risks for adynamic bone.

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