Open AccessEndotoxemia is Related to Systemic Inflammation and Atherosclerosis in Peritoneal Dialysis Patients
Author(s) -
CheukChun Szeto,
Bonnie ChingHa Kwan,
KaiMing Chow,
Ka-Bik Lai,
Kwok-Yi Chung,
ChiBon Leung,
Philip KamTao Li
Publication year - 2008
Publication title -
clinical journal of the american society of nephrology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.755
H-Index - 151
eISSN - 1555-905X
pISSN - 1555-9041
DOI - 10.2215/cjn.03600807
Subject(s) - medicine , peritoneal dialysis , systemic inflammation , inflammation , intensive care medicine
Systemic inflammatory state is a hallmark of peritoneal dialysis (PD) patients, but its etiology remains obscure. Because circulating microbial products are an important cause of systemic immune activation in other conditions such as HIV infection, it was hypothesized that endotoxemia is a cause of systemic inflammatory state and atherosclerosis in PD patients.