Circulating Bacterial-Derived DNA Fragments and Markers of Inflammation in Chronic Hemodialysis Patients | Zendy

Maurizio Bossola | Zendy; Maurizio Sanguinetti | Zendy; Donata Scribano | Zendy; Cecilia Zuppi | Zendy; Stefania Giungi | Zendy; Giovanna Luciani | Zendy; Riccardo Torelli | Zendy; Brunella Posteraro | Zendy; Giovanni Fadda | Zendy; Luigi Tazza | Zendy

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Circulating Bacterial-Derived DNA Fragments and Markers of Inflammation in Chronic Hemodialysis Patients

Author(s) -

Maurizio Bossola,

Maurizio Sanguinetti,

Donata Scribano,

Cecilia Zuppi,

Stefania Giungi,

Giovanna Luciani,

Riccardo Torelli,

Brunella Posteraro,

Giovanni Fadda,

Luigi Tazza

Publication year - 2009

Publication title -

clinical journal of the american society of nephrology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.755

H-Index - 151

eISSN - 1555-905X

pISSN - 1555-9041

DOI - 10.2215/cjn.03490708

Subject(s) - medicine , hemodialysis , c reactive protein , peripheral blood mononuclear cell , dialysis , body fluid , inflammation , gastroenterology , venous blood , dialysis tubing , immunology , pathology , biology , membrane , biochemistry , in vitro , genetics

Bacterial-derived DNA fragments (BDNAs) have been shown to be present in dialysis fluid, to pass through dialyzer membranes, and to induce IL-6 (IL-6) in mononuclear cells. The present study aimed at assessing the eventual presence of BDNAs in the blood of hemodialysis (HD) patients and if this is associated with markers of chronic inflammation.

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