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Efficacy and Safety of Treatment with Rituximab for Difficult Steroid-Resistant and -Dependent Nephrotic Syndrome
Author(s) -
Ashima Gulati,
Aditi Sinha,
Stanley C. Jordan,
Pankaj Hari,
Amit Kumar Dinda,
Sonika Sharma,
Rahul Srivastava,
Asha Moudgil,
Arvind Bagga
Publication year - 2010
Publication title -
clinical journal of the american society of nephrology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.755
H-Index - 151
eISSN - 1555-905X
pISSN - 1555-9041
DOI - 10.2215/cjn.03470410
Subject(s) - rituximab , medicine , nephrotic syndrome , refractory (planetary science) , complete remission , gastroenterology , surgery , chemotherapy , lymphoma , physics , astrobiology
The treatment of idiopathic nephrotic syndrome is often complicated by a refractory and relapsing course, with risk of drug toxicity and progressive renal failure. We report the efficacy and safety of rituximab in patients with steroid-resistant (SRNS) and steroid-dependent nephrotic syndrome (SDNS) refractory to standard therapy.

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