Bone and Mineral Disease in Kidney Transplant Recipients | Zendy

Pascale Khairallah | Zendy; Thomas L. Nickolas | Zendy

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Bone and Mineral Disease in Kidney Transplant Recipients

Author(s) -

Pascale Khairallah,

Thomas L. Nickolas

Publication year - 2021

Publication title -

clinical journal of the american society of nephrology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.755

H-Index - 151

eISSN - 1555-905X

pISSN - 1555-9041

DOI - 10.2215/cjn.03410321

Subject(s) - medicine , bone mineral , vitamin d and neurology , epidemiology , metabolic bone disease , transplantation , hyperparathyroidism , kidney transplantation , vitamin d deficiency , bone disease , disease , kidney disease , risk factor , osteoporosis , intensive care medicine

After kidney transplantation, mineral and bone disorders are associated with higher risk of fractures and consequent morbidity and mortality. Disorders of calcium and phosphorus, vitamin D deficiency, and hyperparathyroidism are also common. The epidemiology of bone disease has evolved over the past several decades due to changes in immunosuppressive regimens, mainly glucocorticoid minimization or avoidance. The assessment of bone disease in kidney transplant recipients relies on risk factor recognition and bone mineral density assessment. Several drugs have been trialed for the treatment of post-transplant mineral and bone disorders. This review will focus on the epidemiology, effect, and treatment of metabolic and skeletal derangements in the transplant recipient.

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